Hey Jim,
I know what you mean. My second monitor, a Dell 19" flat panel, is against the left wall, at a right angle to my main monitor. A 42" Panasonic Viera Plasma TV. To the right of that is my full tower case. On the floor below that is my second computer. And I want to get a second 42" monitor for the other half of my cockpit.
Yes, it's very cozy at my controls, which are also clamped to the desk. (I can't really see the desk, but it's under there somewhere).